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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPD1
All Species:
64.24
Human Site:
S225
Identified Species:
94.22
UniProt:
P10809
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10809
NP_002147.2
573
61055
S225
K
F
D
R
G
Y
I
S
P
Y
F
I
N
T
S
Chimpanzee
Pan troglodytes
XP_001169030
573
61022
S225
K
F
D
R
G
Y
I
S
P
Y
F
I
N
T
S
Rhesus Macaque
Macaca mulatta
XP_001082397
576
61283
S225
K
F
D
R
G
Y
I
S
P
Y
F
I
N
T
S
Dog
Lupus familis
XP_536016
573
60977
S225
K
F
D
R
G
Y
I
S
P
Y
F
I
N
T
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_034607
573
60937
S225
K
F
D
R
G
Y
I
S
P
Y
F
I
N
T
S
Rat
Rattus norvegicus
P63039
573
60937
S225
K
F
D
R
G
Y
I
S
P
Y
F
I
N
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL72
573
60954
S225
K
F
D
R
G
Y
I
S
P
Y
F
I
N
T
A
Frog
Xenopus laevis
NP_001083970
579
61616
S225
K
F
D
R
G
Y
I
S
P
Y
F
I
N
T
A
Zebra Danio
Brachydanio rerio
NP_851847
575
61178
S225
K
F
D
R
G
Y
I
S
P
Y
F
I
N
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02649
573
60790
S221
K
F
D
R
G
Y
I
S
P
Y
F
I
N
S
S
Honey Bee
Apis mellifera
XP_392899
570
60394
S220
K
F
D
R
G
Y
I
S
P
Y
F
I
N
S
S
Nematode Worm
Caenorhab. elegans
P50140
568
60082
S216
K
F
D
R
G
Y
I
S
P
Y
F
I
T
S
A
Sea Urchin
Strong. purpuratus
XP_795205
586
62222
S231
K
F
D
R
G
Y
I
S
P
Y
F
I
N
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43298
576
60917
S234
K
L
D
R
G
Y
I
S
P
Y
F
I
T
N
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29197
577
61262
S231
K
L
D
R
G
Y
T
S
P
Y
F
I
T
N
Q
Baker's Yeast
Sacchar. cerevisiae
P19882
572
60733
S222
R
F
D
R
G
F
I
S
P
Y
F
I
T
D
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
98
N.A.
97.5
97.5
N.A.
N.A.
94
89.4
87.3
N.A.
74
74.6
71
74.9
Protein Similarity:
100
100
98.7
98.9
N.A.
98.2
98.2
N.A.
N.A.
97.7
94.9
94.4
N.A.
86.3
86
82.3
87.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
93.3
93.3
80
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
100
93.3
93.3
Percent
Protein Identity:
N.A.
58.3
N.A.
57.8
55.6
N.A.
Protein Similarity:
N.A.
76.9
N.A.
76.4
73.3
N.A.
P-Site Identity:
N.A.
80
N.A.
66.6
66.6
N.A.
P-Site Similarity:
N.A.
80
N.A.
66.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
100
0
0
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
88
0
0
0
7
0
0
0
0
100
0
0
0
0
% F
% Gly:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
94
0
0
0
0
100
0
0
0
% I
% Lys:
94
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
75
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
13
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
7
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
25
57
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
0
0
25
57
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
94
0
0
0
100
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _